InitalCommit

2025-11-16 10:30:26 +01:00
parent 8b0b73bba8
commit d2e409d10f
73 changed files with 3209 additions and 0 deletions
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+using System;
+using System.Collections.Generic;
+using System.Linq;
+using System.Text;
+using System.Threading.Tasks;
+using static System.Net.WebRequestMethods;
+
+namespace BaseCellSimulation.Enzyms.Cytosol
+{
+    public class PhosphoFructokinase : InternalEnzym
+    {
+        public PhosphoFructokinase()
+        {
+            Km = 0.2;
+            Vmax = 7;
+
+            KmRange = new(0.05, 0.5);
+            VmaxRange = new(1, 25);
+        }
+
+        public double Ki_ATP_PFK    { get; set; }
+        public double Ka_AMP_PFK    { get; set; }
+        public double h_AMP         { get; set; }
+        public double h_ATP         { get; set; }
+
+        public override void ApplyChanges(CellRessources res, double dt)
+        {
+            double used = Math.Min(rate * dt, Math.Min(res.Res.Energy.ATP, res.Res.Carbon.F6P));
+            res.Res.Carbon.F6P     -= used;
+            res.Res.Carbon.FBP     += used;
+            res.ConsumeATP(used);
+            res.Res.Ions.Protons += used;
+        }
+
+        public override void ComputeRate(Resources res)
+        {
+            double inhibition = 1.0 / (1.0 + Math.Pow(res.Energy.ATP / Ki_ATP_PFK, h_ATP)); // Hemmung durch ATP
+            double activation = 1.0 + Math.Pow(res.Energy.AMP / Ka_AMP_PFK, h_AMP);         // Aktivierung durch AMP
+            rate = Michaelis_Menten(res.Carbon.F6P, Vmax * inhibition * activation, Km);
+        }
+    }
+}