InitalCommit

2025-11-16 10:30:26 +01:00
parent 8b0b73bba8
commit d2e409d10f
73 changed files with 3209 additions and 0 deletions
@@ -0,0 +1,54 @@
+using System;
+using System.Collections.Generic;
+using System.Linq;
+using System.Text;
+using System.Threading.Tasks;
+
+namespace BaseCellSimulation.Enzyms.Mytochondrion
+{
+    public class OxPhosEnzyme : InternalEnzym
+    {
+        public double PO_Ratio { get; set; } = 2.5;
+
+        public OxPhosEnzyme()
+        {
+            Vmax = 0.8;
+            Km = 0.01;
+
+        }
+
+        public override void ApplyChanges(CellRessources res, double dt)
+        {
+            double usedNADH = Math.Min(rate * dt, res.Res.Energy.NADH);
+            if (usedNADH <= 0) return;
+
+            res.TransferNADH(usedNADH, true);
+
+            double o2Consumed = 0.5 * usedNADH;
+            res.Res.Oxygen = Math.Max(0.0, res.Res.Oxygen - o2Consumed);
+
+            double atpMade = PO_Ratio * usedNADH;
+            res.RegenerateATP(atpMade);
+
+            // ROS-Produktion
+            double rosFactor = Math.Min(1.0, res.Res.Oxygen / 2.0);
+            res.Res.Ions.H2O2 += usedNADH * 0.001 * rosFactor;
+            res.Res.Protein.Waste += usedNADH * 0.001 * rosFactor;
+        }
+
+        public override void ComputeRate(Resources res)
+        {
+            double nadh = res.Energy.NADH;
+            Michaelis_Menten(nadh);
+
+            // Begrenzung durch O2
+            double o2Limit = Math.Min(1.0, res.Oxygen / 0.05);
+            rate *= o2Limit;
+
+            // ATP/ROS Feedback
+            double atpFactor = Math.Clamp(res.Energy.ATP / 0.5, 0.0, 1.0);
+            double wasteFactor = 1.0 / (1.0 + res.Protein.Waste / 10.0);
+            rate *= atpFactor * wasteFactor;
+        }
+    }
+}