InitalCommit

2025-11-16 10:30:26 +01:00
parent 8b0b73bba8
commit d2e409d10f
73 changed files with 3209 additions and 0 deletions
@@ -0,0 +1,33 @@
+using System;
+using System.Collections.Generic;
+using System.Linq;
+using System.Text;
+using System.Threading.Tasks;
+
+namespace BaseCellSimulation.Enzyms.Nucleus
+{
+    public class PARP1 : InternalEnzym
+    {
+        private const double EnergyCostATP = 0.3;
+
+        public PARP1()
+        {
+            Km = 0.02;
+            Vmax = 0.4;
+        }
+
+        public override void ApplyChanges(CellRessources res, double dt)
+        {
+            double dRepair = Math.Min(rate * dt, res.Res.Protein.DNA_damage);
+            dRepair = res.Res.Energy.NAD >= dRepair * EnergyCostATP ? dRepair : res.Res.Energy.NAD / EnergyCostATP;
+            res.Res.Energy.NAD -= dRepair * EnergyCostATP;
+            res.Res.Energy.NADH += dRepair * 0.2;
+            res.Res.Protein.DNA_damage -= dRepair * 0.8; 
+        }
+
+        public override void ComputeRate(Resources res)
+        {
+            Michaelis_Menten(res.Protein.DNA_damage);
+        }
+    }
+}