InitalCommit

2025-11-16 10:30:26 +01:00
parent 8b0b73bba8
commit d2e409d10f
73 changed files with 3209 additions and 0 deletions
@@ -0,0 +1,70 @@
+using BaseCellSimulation.Enzyms;
+using BaseCellSimulation.Enzyms.Membrane;
+using BaseCellSimulation.Enzyms.Membrane.GLUT;
+
+namespace BaseCellSimulation
+{
+    /// <summary>
+    /// Cell membrane small leakage and passive disposal of waste
+    /// </summary>
+    /// <param name="cellname"></param>
+    /// <param name="glucoseImportRate"></param>
+    /// <param name="oxygenImportRate"></param>
+    /// <param name="wasteOuttakeRate"></param>
+    public class Membrane : Organell
+    {
+        public readonly List<MembranEnzyme> enzyms = new List<MembranEnzyme>();
+        public readonly List<GLUT1> glutTransporters = new List<GLUT1>();
+        private readonly string name;
+
+        public Membrane() : this("Membrane") { }
+
+        public Membrane(string cellname)
+        {
+            this.name = cellname;
+            enzyms.Add(new KLeakChannel());
+            enzyms.Add(new MCT());
+            enzyms.Add(new NaK_ATPase());
+            enzyms.Add(new NCX());
+            enzyms.Add(new PMCA());
+            // Add GLUT transporters
+            glutTransporters.Add(new GLUT1());
+        }
+
+        public string getName()
+        {
+            return name;
+        }
+
+        public void applyChanges(CellRessources res, double dt)
+        {
+
+            foreach (MembranEnzyme enzyme in enzyms)
+            {
+                enzyme.ApplyChanges(res, dt);
+            }
+            foreach (GLUT1 glut in glutTransporters)
+            {
+                glut.ApplyChanges(res, dt);
+            }
+            // --- 5. Kleine Verluste anderer Stoffe (Diffusionslecks) ---
+            res.Res.Carbon.Glucose = Math.Max(0, res.Res.Carbon.Glucose - 0.001 * dt);
+            res.Res.Oxygen = Math.Max(0, res.Res.Oxygen - 0.001 * dt);
+        }
+
+        public void calculateRate(CellRessources res)
+        {
+            foreach (MembranEnzyme enzyme in enzyms)
+            {
+                double gradient = enzyme.CalculateGradient(res);
+                enzyme.ComputeRate(gradient, res.Env);
+            }
+            double glutGradient = glutTransporters[0].CalculateGradient(res);
+
+            foreach (GLUT1 glut in glutTransporters)
+            {
+                glut.ComputeRate(glutGradient, res.Env);
+            }
+        }
+    }
+}