using System;
using System.Collections.Generic;
using System.Linq;
using System.Text;
using System.Threading.Tasks;
using static System.Net.WebRequestMethods;

namespace BaseCellSimulation.Enzyms.Cytosol
{
    public class PhosphoFructokinase : InternalEnzym
    {
        public PhosphoFructokinase()
        {
            Km = 0.2;
            Vmax = 7;

            KmRange = new(0.05, 0.5);
            VmaxRange = new(1, 25);
        }

        public double Ki_ATP_PFK    { get; set; }
        public double Ka_AMP_PFK    { get; set; }
        public double h_AMP         { get; set; }
        public double h_ATP         { get; set; }

        public override void ApplyChanges(CellRessources res, double dt)
        {
            double used = Math.Min(rate * dt, Math.Min(res.Res.Energy.ATP, res.Res.Carbon.F6P));
            res.Res.Carbon.F6P     -= used;
            res.Res.Carbon.F1_6BP     += used;
            res.ConsumeATP(used);
            res.Res.Ions.Protons += used;
        }

        public override void ComputeRate(Resources res)
        {
            double inhibition = 1.0 / (1.0 + Math.Pow(res.Energy.ATP / Ki_ATP_PFK, h_ATP)); // Hemmung durch ATP
            double activation = 1.0 + Math.Pow(res.Energy.AMP / Ka_AMP_PFK, h_AMP);         // Aktivierung durch AMP
            rate = Michaelis_Menten(res.Carbon.F6P, Vmax * inhibition * activation, Km);
        }
    }
}